Cardiac Biomarker ELISA's

Life Diagnostics, Inc. manufactures ELISA kits for measurement of cardiac troponin-I, myoglobin and fatty acid binding protein (FABP) in species including mouse, rat, rabbit, dog pig and monkey. A list of our cardiac biomarker ELISA's is shown below. Kit details and instructions can be obtained by clicking on the "insert" buttons. Literature references are listed at the bottom of this page. Orders may be placed online or by phone, fax or email.

Cardiac Troponin-I ELISA Kits

Kit Name

Kit Insert

Catalog #

Quantity

Unit Price

 

Human Cardiac Tn-I 96-well ELISA
(2 - 75 ng/ml)

insert

2010

1 x 96-well

$375

2 x 96 well

$700

4 x 96-well

$1300

Mouse Cardiac Tn-I 96-well ELISA
(For use with serum, 0.156 - 10 ng/ml)

insert

2010-1-HS

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Mouse Cardiac Tn-I 96-well ELISA
(For use with plasma, 0.078 - 5 ng/ml)

insert

2010-1-HSP

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Rat Cardiac Tn-I 96-well ELISA
(For use with serum, 0.156 - 10 ng/ml)

insert

2010-2-HS

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Rat Cardiac Tn-I 96-well ELISA
(For use with plasma, 0.078 - 5 ng/ml)

insert

2010-2-HSP

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Dog Cardiac Tn-I 96-well ELISA
(0.156 - 10 ng/ml)

insert

2010-3

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Pig Cardiac Tn-I 96-well ELISA
(0.156 - 10 ng/ml)
 

insert

2010-4

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Monkey Cardiac Tn-I 96-well ELISA
(0.156 - 10 ng/ml)

insert

2010-5

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Rabbit Cardiac Tn-I 96-well ELISA
(0.39 -25 ng/ml)

insert

2010-6

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

 

Myoglobin ELISA Kits

Kit Name

Kit Insert

Catalog #

Quantity

Unit Price

Human Myoglobin 96-well ELISA
(5 -1000 ng/ml)

insert

2110

1 x 96-well

$375

2 x 96 well

$700

4 x 96-well

$1300

Mouse Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)
 

insert

2110-1

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Mouse Myoglobin 96-well ELISA
(New higher sensitivity version, for serum, plasma & urine samples (3.9 - 250 ng/ml)

insert

2110-1-N

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Rat Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)

insert

2110-2

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Rat Myoglobin 96-well ELISA
(New higher sensitivity version, for serum, plasma & urine samples, 1.56 - 100 ng/ml)

insert

2110-2-N

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Rabbit Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)

insert

2110-3

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Dog Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)

insert

2110-4

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Dog Myoglobin 96-well ELISA
(New higher sensitivity version, for serum, plasma & urine samples, 3.9 - 250 ng/ml)

insert

2110-4-N

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Pig Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)

insert

2110-5

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

Monkey Myoglobin 96-well ELISA
(7.8 - 500 ng/ml)

insert

2110-6

1 x 96-well

$425

2 x 96 well

$800

4 x 96-well

$1500

 

Fatty Acid Binding Protein ELISA Kits

Kit Name

Kit Insert

Catalog #

Quantity

Unit Price

 

Human Cardiac FABP 96-well ELISA
1 - 100 ng/ml)

insert

2310

1 x 96-well

$375

2 x 96 well

$700

4 x 96-well

$1300

Mouse Cardiac FABP 96-well ELISA
(0.78 - 25 ng/ml)

insert

2310-1

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Rat Cardiac FABP 96-well ELISA
(0.78 - 25 ng/ml)

insert

2310-2

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Dog Cardiac FABP 96-well ELISA
(0.31 - 20 ng/ml)

insert

2310-4

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Pig Cardiac FABP 96-well ELISA
(0.78 - 25 ng/ml)

insert

2310-5

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

Rabbit Cardiac FABP 96-well ELISA
(1.56 - 100 ng/ml)

insert

2310-6

1 x 96-well

$450

2 x 96 well

$800

4 x 96-well

$1500

The figure below illustrates the utility of our animal troponin-I, myoglobin and FABP kits. It shows the levels of the respective markers in plasma obtained from a rabbit cardiac ischemia/reperfusion model. Plasma samples were collected before/during ischemia and at various times after reperfusion. Consistent with clinical findings in humans, it can be seen that the (i) levels of myoglobin and FABP increase prior to those of troponin-I and (ii) troponin-I levels remain elevated longer than do those of myoglobin and FABP.

Literature Citations

Mouse cTnI Publications

  1. Morrison RR, Tan XL, Ledent C, Mustafa SJ and Hifmann PA. Targeted deletion of A2A adenosine receptors attenuates the protective effects of myocardial postconditioning. Am J Physiol Heart Circ Physiol. 293:H2523-H2529 (2007)

  2. Engle, SK et al.  Strain differences in serum cardiac troponin-I concentration and myocardial necrosis after isoproterenol treatment in mice.  Abstract No. 383.  The Toxicologist CD — An official Journal of the Society of Toxicology, Volume 96, Number S-1, March 2007.

  3. Hou G, Dick R, Zeng C, Brewer GJ., Comparison of lowering copper levels with tetrathiomolybdate and zinc on mouse tumor and doxorubicin models. Translational Research 148:309-314 (2006)

  4. Huber SA, Feldman AM and Sartini D., Coxsackievirus B3 induces T regulatory cells, which inhibit cardiomyopathy in tumor necrosis factor-a transgenic mice. Circ Res. 99:1109-1116 (2006)

  5. Mullick A, Leon Z, Min-Oo G, Berghout J, Lo R, Daniels E and Gros P. Cardiac failure in C5-deficient mice after Candida albicans infection. Infection and Immunity. 74(8):4439-4451 (2006)

  6. Hou G, Dick R, Abrams GD, Brewer GJ., Tetrathiomolybdate protects against cardiac damage by doxorubicin in mice. J Lab Clin Med.146(5):299-303 (2005)

  7. Tao L, Liu H-R, Gao F, Qu Y, Christopher TA, Lopez BL and Ma XL. Mechanical traumatic injury without circulatory shock causes cardiomyocyte apoptosis: rol of reactive nitrogen and reactive oxygen species. Am J Heart Circ Physiol.  288:H2811-H2818 (2005)


Rat cTnI Publications

  1. Legare JF, Oxner A, Heimrath O, Myers T and Currie RW. Heat Shock treatment results in increased recruitment of labeled PMN following myocardial infarction. Am J Physiol Heart Circ Physiol. 293(5):H3210-5 (2007)

  2. Chopra M and Sharma AC. Distinct cardiodynamic and molecular chracteristics during early and late stages of sepsis-induced myocardial dysfunction. Life Sciences. epub. July 2007

  3. Liu J, Pang Y, Chang T, Bounelis P, Chatham JC, and Marchase RB. Increased hexoseamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia. J Mol. Cell Cardiol. 40 303-312 (2006)

  4. Wang P and Chatham JC. Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart. Am J Physiol Endocrinol Metab 286:E725-E736 (2004)
     

Rabbit cTnI Publications

  1. Booth EA, and Lucchesi BR. Medroxyprogesterone acetate prevents the cardioprotective and anti-inflammatory effects of 17beta-estradiol in an in vivo model of myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol. 293(3):H1408-15 (2007)

  2. Lauver DA, Booth EA, White AJ, Poradosu E & Lucchesi BR. Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis. J Pharm. Exp. Ther. 312(2):794-800 (2005)

  3. Lauver DA, Lockwood SF and Lucchesi BR. Disodium disuccinate astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. J Pharm. Exp. Ther. 314(2):686-692 (2005)

  4. Booth EA, Obeid NR and Lucchesi BR. Activation of estrogen receptor-alpha protects the in vivo rabbit heart from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 289(5):H2039-47 (2005)


Pig cTnI Publications

  1. Wu D, Bassuk J, Arias J, Doods H and Adams JA. Cardiovascular effects of Na+/H+ exchanger inhibition with BIIB513 following hypovolemic circulatory shock. Shock 23(3):269-274 (2005)

 

Life Diagnostics Inc., P.O. Box 5205, West Chester PA 19380 u 610.431.7707 [phone] u 610.431.7817 [fax] u info@lifediagnostics.com

 

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