Skeletal Muscle Biomarkers

Skeletal Muscle Biomarker ELISA Kits  |  Purified Skeletal Muscle Proteins

As a result of skeletal muscle injury, protein biomarkers are released into the blood stream. Measurement of the levels of these proteins allows the extent of skeletal muscle damage to be assessed. We offer a range of skeletal muscle biomarker ELISA kits in addition to purified skeletal muscle biomarkers.

We have recently introduced mouse and rat skeletal muscle troponin-I ELISA kits (catalog numbers 2020-1-SK and 2010-2-SK). Both kits specifically recognize the fast twitch isoform of skeletal muscle troponin-I in serum or plasma and can be used to assess skeletal muscle damage even in the presence of cardiac damage. To the best of our knowledge, Life Diagnostics, Inc. is the only commercial supplier of skeletal muscle troponin-I ELISA kits for rats and mice.

In addition to the skeletal muscle troponin-I kits we also offer ELISA kits for myoglobin, fatty acid binding protein (FABP) and myosin light chain-1 (MLC-1) in serum or plasma of species including mice, rats, dogs, rabbits, pigs and monkeys. Myoglobin, FABP and MLC-1 are useful biomarkers of skeletal muscle damage. However, unlike skeletal muscle troponin-I, myoglobin and FABP are nonspecific because both are expressed in cardiac muscle as well as skeletal muscle. When using myoglobin and FABP as skeletal muscle biomarkers it is therefore important to exclude, or control for, cardiac damage. The advantages of myoglobin and FABP are that they are usually released into the blood at much higher levels than found for skeletal muscle troponin-I, facilitating easier detection.

For pricing and specific product information please follow the links at the top of the page